A new study has found a correlation between high-fat, high-sugar Western diets and the development of non-alcoholic fatty liver disease. The study identified the western diet-induced microbial and metabolic contributors to liver disease.
A new study has found a correlation between high-fat, high-sugar Western diets and the development of non-alcoholic fatty liver disease. The study identified the western diet-induced microbial and metabolic contributors to liver disease.
The gut and liver have a close anatomical and functional connection via the portal vein. Unhealthy diets change the gut microbiota, resulting in the production of pathogenic factors that impact the liver.
High sugar and fat diet can cause liver disease: Research
WHAT?
A new study from the University of Missouri School of Medicine has found a correlation between high-fat, high-sugar Western diets and the development of non-alcoholic fatty liver disease , the main cause of chronic liver disease .
HOW?
The gut and liver have a close anatomical and functional connection via the portal vein. Unhealthy diets change the gut microbiota, resulting in the production of pathogenic factors that impact the liver.
By feeding mice foods high in fat and sugar, the research team discovered that the mice developed a gut bacteria called Blautia producta and a lipid that caused liver inflammation and fibrosis.
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As part of this study, the researchers tested treating the mice with an antibiotic cocktail administered via drinking water. They found that the antibiotic treatment reduced liver inflammation and lipid accumulation, resulting in a reduction in fatty liver disease.